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KMID : 0644320020080010093
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Journal of Korean Oriental Oncology
2002 Volume.8 No. 1 p.93 ~ p.101
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A Study on the Immune activaty of Phellinus Linteus Extracts
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Lim Eui-Su
Choi Byung-Lyul
Yoo Hwa-Seung
Lee Yong-Yeon
Seo Sang-Hoon
Cho Jung-Hyo
Lee Yeon-Weol
Son Chang-Gue
Cho Chong-Kwan
Lee Yong-Koo
Song Kee-Cheol
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Abstract
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Objectives: This experimental study was carried out to evaluate the effects of Phellinus Linteus on immune activation.
Methods: In order to investigate the effect of Phellinus Linteus, the following was performed: The fraction of CD4?
,CD8?, CD19? in splenic cell, gene expression of IL-12 (p35), IL-12 (p40) , IFN-r and splenic cell proliferation by PL-E.
Results: PL-E helped ,CD4?,CD8?, CD19? expression more effectively compared with control group. PL-E helped IL-12 (p35), IL-12 (p40), IFN-r gene expression in splenic cells more effectively compared with control group. PL-E proliferated splenic cells more effectively compared with control group.
Conclusions: It is suggested that PL-E is able to activate immune response system.
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KEYWORD
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PhellinusLinteus, Immuneactivation, spleniccell, IL-12, IFN-r, proliferation
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